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Articaine hydrochloride is a selective inhibitor of voltage-gated sodium channels, demonstrating local anesthetic activity by blocking nerve impulse conduction. It also exhibits anti-inflammatory functions by inhibiting NF-κB activation and NLRP3 inflammasome pathways. It is used in the study of dental local anesthesia and inflammatory-related diseases.
Inhibits voltage-gated sodium channels
Exhibits local anesthetic activity
Inhibits NF-κB activation and NLRP3 inflammasome pathways
Reduces inflammatory factors like TNF-α, IL-6, and IL-1β
Ameliorates LPS-induced acute kidney injury in animal models
Can enhance anesthetic effect in zebrafish model
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Olcegepant hydrochloride is the hydrochloride salt of olcegepant, a potent and selective non-peptide antagonist of the calcitonin gene-related peptide 1 (CGRP1) receptor used in neuroscience and pharmacology research. It is supplied in ready-to-use solution and solid+solvent formats for flexible laboratory use and includes analytical documentation for verification.
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3,4-O-Isopropylidene-shikimic acid is a natural product that can be isolated from the whole plants of *Hypericum wightianum*. It exhibits anti-inflammatory and antioxidant activities.
Natural product
Isolated from *Hypericum wightianum*
Anti-inflammatory effect
Antioxidant activities
Appearance: Solid
Color: Off-white to light yellow
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Also available in 1 mL, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. 2-Aminooctadecane-1,3,4-Triol (Phytosphingosine) is a natural product. Purity ≥98%
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Pentane-1,3,5-triol is a small-molecule triol used as a drug intermediate in the synthesis of active pharmaceutical compounds. It has molecular formula C5H12O3 and a molecular weight of 120.15 g/mol (CAS 4328-94-3). The material is supplied for laboratory research use; batch-specific analytical reports are available for identity and purity.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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